Randevu 0216 449 09 41
Prof. Dr. Cengiz BAHADIR

Other Disorders

Other Areas of Use and Research for Transcranial Magnetic Stimulation

Transcranial magnetic stimulation (TMS) therapy can increase or suppress the activity of the nerve cells in the application site. And this makes it an appropriate therapy for many neurological disorders. TMS is an FDA approved treatment choice for depression covered by insurance agencies in many countries including USA. There are over 600 sites providing depression treatment via TMS in USA. The efficacy of TMS has been scientifically established in hemiplegia (stroke), speech disorders secondary to paralysis (aphasia), tinnutus, distonia (writer’s cramp, musician’s cramp), central pain disorders other than depression.diger

TMS is still on trial stage for many neurological disorders that are not curable with medications or the medications are not efficient enough to provide benefit. Although the majority of the studies show positive outcomes, TMS therapy is not still among the standardized methods.
TMS therapy is primarily administered for movement disorders. Mainly such as hand tremor, voluntary movement disorders, ataxia and some other rare movement disorders. Ataxia is a movement disorder that affects muscle coordination, disrupts balance and impairs walking. According to a recent study conducted in the USA, TMS therapy has been the very first to improve walking on an ataxia case as a result of damage to the central nervous system. It is extremely important to provide an objective level of improvement, although not yet completely, with TMS therapy in incurable cases like ataxia. Essential tremor is a progressive neurological disorder with low rates of treatment success with medications. A study conducted with TMS on essential tremor cases provided positive outcomes. Deep brain stimulation with special shaped coils newly developed on TMS therapy is currently under experimenting stage. The odds are in favor for the treatment of such disorders when we can selectively stimulate the cortex, i.e. the outer layer of brain. Multiple sclerosis is another disorder TMS therapy provides benefit. And it has a very inconsistent manifestation. It can cause many various clinical conditions ranging from visual disorder and diplopia to imbalance, from hemiplegia to paralysis, from cognitive function disorders to depression. TMS therapy is administered based on the manifestations, not the disorder itself. For example, if the patient is suffering from depression secondary to MS, a depression treatment is provided. If the patient is suffering from wrist drop, we administer treatment to the motor cortex of the brain which is related to the movement functions. MS is usually a progressive disorder. TMS therapy may not be sufficient to prevent seizures but it can at least recover the loss of function due to the disorder. We are now able to determine the impacts of MS on nervous system responsible for the management of movement thanks for the special tests (MEP test) with TMS. This test provides valuable insights on the recovery potential of the patient.

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Studies are conducted to understand the physiopathology of the disorder in pediatric patients, especially pediatric patients with cerebral palsy (CP). TMS has only recently been used on pediatric patients with CP. There is not sufficient data on this disorder yet. There are still studies conducted for some spinal cord diseases, amyotrophic lateral sclerosis and other motor neuron diseases.

diger2TMS therapy has been experimented in the treatment of epilepsy, schizophrenia, bipolar disorder and some behavioral disorders with positive outcomes. TMS appears to be administered in the treatment of various psychiatric disorders other than depression.
Over 10,000 studies have been conducted with TMS and each day we are amazed with the outcomes of new studies. The results show that TMS therapy will soon be a standard choice in the treatment of neurological and psychiatric disorders.